| Title | [Protocole with GnRH-antagonist and ovulation trigger with GnRH-agonist in risk patients--a reliable method of prophylactic of OHSS] |
| Source | Akush Ginekol (Sofiia) 2008; 47(4):16-9. |
| Abstract | OHSS is a serious complication of COH and PCOS is a major risk factor for its development.
OBJECTIVE: The objective of this study is to evaluate the effect of the application of GnRH-agonist in patients with PCOS for triggering the ovulation and prophylactic of OHSS.
MATERIALS AND METHODS: In the present study we evaluated 29 patients with PCOS who had been stimulated for the purposes of ART with gonadotrophins and GnRH-antagonist and application of GnRH-agonist (Decapeptyl; Dipherilyn-0.2 mg) instead of HCG.
RESULTS: From the observed group one patient developed severe form of late OHSS. The average number of aspirated oocytes was 22.5 and the clinical pregnancy was 46.8%.
CONCLUSION: The application of protocole with GnRH-antagonist and triggering of the ovulation with GnRH-agonist is a good alternative when a high risk of development of OHSS exists and our results prove that. |
| Language | bul |
| Pub Type(s) | English Abstract
Journal Article
|
| PubMed ID | 19227761 |
